The PubMed interface changed quite a bit in 2011 and both the main tutorials and the Quick Tours have been updated.
• PubMed's scope and content.
• Understand how the MeSH vocabulary is used to describe and retrieve citations.
• Build a search using MeSH and PubMed tools (Details, Limits, History, Search Builder.)
• Manage results: display, sort, the Clipboard, save, print, e-mail and My NCBI filters.
• Save your search strategies.
• Link to full-text articles and other resources.
• Use special queries and other PubMed/NCBI tools.