Today, 20th May, is International Clinical Trials Day. It commemorates the day James Lind started his famous trial on scurvy and is the recognised date for organisations, clinical research professionals and the public to celebrate and acknowledge the importance of research in healthcare.
Frank Moriarty, who is based at the HRB Centre for Primary Care Research at RCSI in Dublin, has written an article in the latest Irish Times health supplement calling for open and transparent clinical trial reporting, in order to eliminate bias towards positive results. He argues that this bias 'can alter the balance of evidence for a drug and make it appear more beneficial that it actually is'. You can read the full article here .
The RCSI library website has links to a wide range of resources on evidence based healthcare. Of particular interest may be the CONSORT website. The main product of the CONSORT group is the CONSORT Statement which is an evidence based, minimum set of recommendations for reporting randomized trials. It offers a standard way for authors to prepare reports of trial findings, facilitating their complete and transparent reporting, reducing the influence of bias on their results and aiding their critical appraisal and interpretation.
The ISRCTN registry , a primary clinical trial registry recognised by WHO and ICMJE that accepts all clinical research studies, may also be of interest as well as clinicaltrials,gov which is maintained by the United States National Library of Medicine (NLM) and provides access to information on publicly and privately supported clinical studies on a wide range of diseases and conditions,
Wellcome Library, London.